Presku: | AAP56215 |
Size: | 100 ug |
Weight: | 50kDa |
Gene: | 57120 |
Format: | Lyophilized powder |
Target: | GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM]. |
Alternative names: | CAL; FIG; GOPC1; PIST; dJ94G16.2 |