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GNPTAB (N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits) Blocking Peptide (the N terminal of GNPTAB)(100ug)

GNPTAB (N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits) Blocking Peptide (the N terminal of GNPTAB)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-GNPTAB Antibody(ARP49815_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP49815
Size: 100ug
Weight: 143kDa
Gene: 79158
Format: Lyophilized powder
Target: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.
Alternative names: DKFZp762B226; GNPTA; ICD; KIAA1208; MGC4170
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