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GluR2 (Ser880) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252549

GluR2 (Ser880) Antibody

The glutamate receptor 2, a homo- or heter0teramer, is an Ionotropic glutamate receptor. L-glutamate acts as an e, Xenopus/Amphibian,citatory neurotransmitter at many synapses in the central nervous system. Binding of the e, Xenopus/Amphibian,citatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The glutamate receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Ser880 has been identified as a PKC phosphorylation site within the C-terminal region of GluR2 and has been shown to differentially regulate the interaction of the PDZ domain-containing proteins GRIP1 and PICK 1.\n

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SPECIFICATIONS

Catalog Number

252549

Size

0.1 ml

Applications

WB

Reactivities

Hum, Mouse, Ch/Bird, Rabbit, ZF/Fish

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser880 of rat GluR2-subunit.

Isotype

Rabbit IgG

Accession

P19491

Additional Info

Glutamate receptor 2; GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2; Gria2; Glur2

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