GLP-2 Antibody

Glucagon-like peptide-2 (GLP-2) is liberated in the intestinal L cells after glucagon processing. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract from the stomach to the colon is the principal target for the GLP-2 action. GLP-2 plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function as well as increasing nutrient disposal. GLP-2 also stimulates intestinal glucose transport and decreases mucosal permeability.