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GIT2 (G protein-coupled receptor kinase interacting ArfGAP 2) Blocking Peptide (the C terminal of GIT2)(100ug)

GIT2 (G protein-coupled receptor kinase interacting ArfGAP 2) Blocking Peptide (the C terminal of GIT2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-GIT2 Antibody (ARP61662_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP61662
Size: 100ug
Weight: 83kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined.
Alternative names: CAT-2; DKFZp686G01261; KIAA0148; MGC760
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