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GFI1 (5D7) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253057

GFI1 (5D7) Antibody

GFI1 (Growth factor independent protein 1) is a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental conte, Xenopus/Amphibian,ts, including hematopoiesis and oncogenesis. It functions as part of a comple, Xenopus/Amphibian, along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. GFl1 is e, Xenopus/Amphibian,pressed in the hematopoietic and lymphoid system, sensory epithelia, lungs and CNS.

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SPECIFICATIONS

Catalog Number

253057

Size

0.1 ml

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human GFI1 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q99684

Clonality

5D7

Additional Info

Zinc finger protein Gfi-1; Growth factor independent protein 1; Zinc finger protein 163; ZNF163; GFI1

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