Supplier:
Aviva Systems Biology IncorporatedGCK antibody - N-terminal region (ARP61473_P050)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum
Format
Lyophilized powder
Presku
ARP61473_P050
Target
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
Weight
51kDa
Gene Id
2645
Alternative Names
FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; MODY2; LGLK
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