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GATA3 (7B5) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253010

GATA3 (7B5) Antibody

GATA3 (GATA binding protein 3) is an enhancer-binding protein containing a zinc finger domain. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. A common TCR regulatory element was identified by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells,Mouse,acrophages, or HeLa cell lines. GATA3 is abundantly e, Xenopus/Amphibian,pressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers.

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SPECIFICATIONS

Catalog Number

253010

Size

0.1 ml

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human GATA3 e, Xenopus/Amphibian,pressed in E. coli. \r<br>

Isotype

Mouse IgG1

Accession

P23771

Clonality

7B5

Additional Info

HDR; Trans-acting T-cell-specific transcription factor GATA-3 ; GATA-binding factor 3

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