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GAT-1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253157

GAT-1 Antibody

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a chloride channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia. GAT-1 is thought to play a key role in epileptogenesis.

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SPECIFICATIONS

Catalog Number

253157

Size

0.1 ml

Applications

IHC

Reactivities

Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat GABA transporter (GAT) 1.

Isotype

Rabbit Ig

Accession

P23978

Additional Info

Sodium- and chloride-dependent GABA transporter 1; GAT-1; Solute carrier family 6 member 1; Slc6a1; Gabt1, Gat-1, Gat1

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