GALNT6 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

Supplier: Aviva Systems Biology Incorporated

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Full length GALNT6 is expressed in E. coli.

Presku:	APL11051
Size:	200ug
Weight:	97
Gene:	11226
Target:	This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
Alternative names:	GalNAcT6; GALNAC-T6