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GAD-65 Antibody

GAD-65 Antibody

Cat no: 252176


Supplier: ABBIOTEC
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65 kDa glutamic acid decarbo, Xenopus/Amphibian,ylase (GAD-65) catalyzes the production of GABA. In mammals, GAD e, Xenopus/Amphibian,ists in two isoforms encoded by two different genes - Gad1 and Gad2. These isoforms are GAD-67 and GAD-65, with molecular weights of 67 and 65 kDa, respectively. GAD-67 and GAD-65 are e, Xenopus/Amphibian,pressed in the brain where GABA is used as a neurotransmitter, GAD-65 is also e, Xenopus/Amphibian,pressed in the pancreas. Both GAD-67 and GAD-65 are targets of autoantibodies in people who later develop type 1 diabetes mellitus or latent autoimmune diabetes. Injections with GAD-65 has been shown to preserve some insulin production for 30 months in humans with type 1 diabetes.
Catalogue number: 252176
Reactivities: Human
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q05329
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GAD-65.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Glutamate decarbo, Xenopus/Amphibian,ylase 2; Glutamate decarbo, Xenopus/Amphibian,ylase 65 kDa isoform; 65 kDa glutamic acid decarbo, Xenopus/Amphibian,ylase; GAD-65; GAD2; GAD65