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GABAA Receptor beta-3 (Ser408/409) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252541

GABAA Receptor beta-3 (Ser408/409) Antibody

Gamma-aminobutyric acid receptor subunit beta-3 (GABAA Receptor, b3) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Phosphorylation of serine 408 and serine 409 within the beta-3 subunit have been shown to be critical for the functional modulation of beta-3 containing recombinant receptors.

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SPECIFICATIONS

Catalog Number

252541

Size

0.1 ml

Applications

WB

Reactivities

Hum, Mouse, Bov, Ch/Bird, Xen/Amph, ZF/Fish

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser408/409 of rat GAGAA receptor, b3.

Isotype

Rabbit IgG

Accession

P63079

Additional Info

Gamma-aminobutyric acid receptor subunit beta-3; GABA(A) receptor subunit beta-3; Gabrb3; Gabrb-3

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