Reactivities: | Human |
Presku: | AAP66172 |
Size: | 100ug |
Weight: | 167kDa |
Gene: | 79443 |
Format: | Lyophilized powder |
Target: | This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). |
Alternative names: | DKFZp779K1152; FLJ13335; MGC126517; MGC126519; RUFY3; ZFYVE7 |