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FOXO4 (forkhead box O4) Blocking Peptide (the C terminal of FOXO4)(100ug)

FOXO4 (forkhead box O4) Blocking Peptide (the C terminal of FOXO4)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-FOXO4 Antibody(ARP32110_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP32110
Size: 100ug
Weight: 54kDa
Gene: 4303
Format: Lyophilized powder
Target: FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
Alternative names: AFX; AFX1; MGC120490; MLLT7
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