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Foxa2 (forkhead box A2) Blocking Peptide (the middle region of Foxa2)(100ug)

Foxa2 (forkhead box A2) Blocking Peptide (the middle region of Foxa2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Foxa2 Antibody(ARP37060_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Mouse
Presku: AAP37060
Size: 100ug
Weight: 48kDa
Gene: 15376
Format: Lyophilized powder
Target: Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.
Alternative names: HNF3-beta; HNF3beta; Hnf-3b; Hnf3b; Tcf-3b; Tcf3b
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