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Follistatin Recombinant Protein (0.005 mg)

Follistatin Recombinant Protein (0.005 mg)

Follistatin is a secreted protein that binds to ligands of the TGF-beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.

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SPECIFICATIONS

Size

0.005 mg

Presku

OPPB00114

Alternative Names

FS; activins-binding protein

SUPPLIER INFO

Aviva Systems Biology Incorporated

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