FKBP1A (FK506 binding protein 1A, 12kDa ) Blocking Peptide (the N terminal of FKBP1A)(100ug)

This is a synthetic peptide designed for use in combination with anti-FKBP1A Antibody (ARP65168_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP65168

Target

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Weight

12kDa

Gene Id

2280

Alternative Names

FKBP-12; FKBP1; FKBP12; FKBP12C; PKC12; PKCI2; PPIASE