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FITC anti-rat CD25

FITC anti-rat CD25

Cat no: 202103


Supplier: BioLegend
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CD25 is a 55 kD glycoprotein also known as IL-2 receptor alpha chain. It is broadly expressed on activated T and B cells, a subset of thymic and splenic dendritic cells, and intestinal epithelial cells in the rat. IL-2 is a critical cytokine involved in lymphocyte proliferation and clonal expansion. IL-2 signaling requires the high affinity IL-2 receptor composed of IL-2 receptor chains alpha, beta, and gamma. The OX-39 antibody weakly inhibits IL-2 binding to the IL-2 receptor and has been shown to block some IL-2 mediated responses in vitro.
Catalogue number: 202103
Reactivities: Rat
Hosts: Mouse
Applications: Flow Cytometry
Size: 100 microg
Clone: OX-39
Gene: 16184
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.5 mg/ml
Antigen: Rat T cell blasts from mixed lymphocyte reactions
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: IL-2Ra, IL-2 receptor chain a