FITC anti-mouse TCR Vgamma2

T cell receptor (TCR) Vgamma2 bearing T lymphocytes make up a significant proportion of gammadelta TCR cells in late fetal and adult peripheral lymphoid tissues. TCR gammadelta T cells may play a role in immunological surveillance for stress-induced self-antigens. The frequency of Vgamma2 expression in different strains varied from 12% to 54% in the TCR gammadelta repertoire. Variations in the levels of Vgamma2+ cells are not associated with MHC haplotype. High Vgamma2 expression is influenced by the TCR-delta locus. Expanding Vgamma2+ TCRgammadelta cells in B6 mice overwhelmingly use a Vdelta7+ delta chain except in the DBA/2 strain.

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SPECIFICATIONS

Catalog Number

137703

Size

50 microg

Applications

FC

Reactivities

Mouse

Clone

UC3-10A6

Antigen

G8 mouse T cells

Gene Id

110067

Isotype

Armenian hamster IgG

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

Vgamma2 T-cell receptor, T cell receptor gamma 2

Regulatory Status

RUO