FITC anti-mouse TCR Vbeta7

The TR310 antibody reacts with the mouse T cell receptor Vbeta7 segment . T cells expressing the alpha/beta T cell receptor use clonally distributed TCRs to recognize cell-bound antigens such as peptide/MHC complexes and viral superantigens. The alpha/beta TCR is an oligomeric TCR complex composed of covalently bound alpha and beta chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3delta, gamma, epsilon, and zeta chains. The TR310 antibody reacts with one such clonally distributed TCR beta chain known as Vbeta7. Vbeta7 is expressed on a small subpopulation of both CD4+ and CD8+ T cells. The TR310 antibody has been used for the identification of Vbeta7 expressing T cells by flow cytometry and immunoprecipitation.