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FITC anti-H2A.X Phospho (Ser139)

FITC anti-H2A.X Phospho (Ser139)

Cat no: 613404


Supplier: BioLegend
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H2A.X is a 14 kD basal histone and a member of the H2 histone family. This nuclear protein is synthesized in the G1 and S phase of the cell cycle and is known to be important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 after double-stranded DNA breaks. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. The 2F3 monoclonal antibody reacts with phosphorylated human H2A.X (Ser139) and has been shown to be useful for Western blotting and immunofluorescence.
Catalogue number: 613404
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Size: 100 tests
Clone: 2F3
Gene: 3014
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent intracellular staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: Modified peptide
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: H2A.x, H2a/x, Histone 2A, Histone 2A.X