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Fibulin 5 (3F10) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252660

Fibulin 5 (3F10) Antibody

FBLN5 (Fibulin 5) is a 448-amino acid multifunctional e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian, protein (~50kDa). It mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a conte, Xenopus/Amphibian,t-specific manner and prevents elastinopathy in vivo. Fibulin-5 is abundantly e, Xenopus/Amphibian,pressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

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SPECIFICATIONS

Catalog Number

252660

Size

0.1 ml

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of Fibulin 5 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q9UB, Xenopus/Amphibian,5\n

Clonality

3F10A5, 3F8A12

Additional Info

Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Urine p50 protein; UP50; DANCE; FBLN5

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