Full length recombinant mature FGF-1 (15.8 kDa, 140 amino acids) expressed in E. coli.FGF-1 (acidic FGF) is a member of the fibroblast growth factor (FGF) family, which binds heparin. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
Applications
1. Use as a supplement in serum-free or reduced serum media for culture of mammalian cells.
2. Studies of the human FGF1 receptor, transmembrane signaling and protein phosphorylation
3. Western blotting control for anti-EGF antibodies