FGR (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) Blocking Peptide (the middle region of FGR)(100ug)

This is a synthetic peptide designed for use in combination with anti-FGR Antibody(ARP54523_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Hum

Format

Lyophilized powder

Presku

AAP54523

Target

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Weight

59kDa

Gene Id

2268

Alternative Names

FLJ43153; MGC75096; SRC2; c-fgr; c-src2; p55c-fgr; p58c-fgr