Supplier:
Aviva Systems Biology IncorporatedFGR antibody - middle region (ARP54523_P050)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum
Format
Lyophilized powder
Presku
ARP54523_P050
Target
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Weight
59kDa
Gene Id
2268
Alternative Names
FLJ43153; MGC75096; SRC2; c-fgr; c-src2; p55c-fgr; p58c-fgr; p55-Fgr; p58-Fgr
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