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FEZ2 Antibody (OAPB00606)

FEZ2 Antibody (OAPB00606)

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, IF, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB00606

Target

(IN) Fasciculation and elongation protein zeta-2

Alternative Names

FEZ2 (IN); Fasciculation and elongation protein zeta-2; zygin 2

SUPPLIER INFO

Aviva Systems Biology Incorporated

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