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FCER1A (Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide) Blocking Peptide (the N terminal of FCER1A)(100ug)

FCER1A (Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide) Blocking Peptide (the N terminal of FCER1A)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-FCER1A Antibody(ARP45203_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP45203
Size: 100ug
Weight: 27kDa
Gene: 2205
Format: Lyophilized powder
Target: The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.
Alternative names: FCE1A; FcERI
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