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Fbxw7 (F-box and WD-40 domain protein 7) Blocking Peptide (the middle region of Fbxw7)(100ug)

Fbxw7 (F-box and WD-40 domain protein 7) Blocking Peptide (the middle region of Fbxw7)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Fbxw7 Antibody(ARP37443_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Mouse
Presku: AAP37443
Size: 100ug
Weight: 70kDa
Gene: 50754
Format: Lyophilized powder
Target: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
Alternative names: 1110001A17Rik; AGO; Cdc4; Fbw7; Fbwd6; Fbx30; Fbxo30; Fbxw6; SEL-10
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