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Fbxo2 (F-box protein 2 ) Blocking Peptide (the C terminal of Fbxo2)(100ug)

Fbxo2 (F-box protein 2 ) Blocking Peptide (the C terminal of Fbxo2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Fbxo2 Antibody (ARP43113_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP43113
Size: 100ug
Weight: 34kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: Fbxo2 is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
Alternative names: FBG1; FBX2; Fbs1; Fbs2; MGC54895; NFB42; Prpl4
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