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FASTK (Human) cDNA (1ug)

FASTK (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human FASTK is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-FASTK polyclonal antibody.
Presku: ANA11143
Size: 1ug
Gene: 10922
Target: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
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