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FasL Antibody

FasL Antibody

Cat no: 250646

Supplier: ABBIOTEC
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Fas ligand (FasL or CD95L) is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptoic signal into cells. FasL is involved in cytoto, Xenopus/Amphibian,ic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis has a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells or both. Defects in FasL are the cause of autoimmune lymphoproliferative syndrome 1B (ALPS1B), a childhood syndrome involving hemolytic anemia and thrombocytopenia.
Catalogue number: 250646
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P48023
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human FasL.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: FasL; Tumor necrosis factor ligand superfamily member 6; Fas antigen ligand; Fas ligand; CD95L protein; Apoptosis antigen ligand; APTL; CD178; FASLG; APT1LG1; FASL; TNFSF6
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