Supplier:
Aviva Systems Biology IncorporatedFAS Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)
Prices direct from Aviva Systems Biology Incorporated
Quick response times
Exclusive Absave savings/discounts
SPECIFICATIONS
Size
200ug
Presku
APL10182
Target
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
Weight
44
Gene Id
355
Alternative Names
APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6
Latest promotions
New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...
Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...
Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...
10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...
For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...
We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!
Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...
Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...
Top suppliers
Agrisera AB
11 products
Biotrend
Biosensis
969 products
ABBIOTEC
3011 products
SDIX
1 products
Spring Bioscience
2291 products
Cell Signaling Technology
4976 products
Rockland Immunochemicals, Inc.
7592 products
Boster Immunoleader
1533 products
Proteintech Group
1 products
OriGene Technologies Inc.
5281 products
Maine Biotechnology Services
227 products
BD (Becton, Dickinson and Company)
1 products
ABNOVA CORPORATION
Randox Life Sciences
1502 products
