Home  >  Products  >  FAM175A (family with sequence similarity 175, member A ) Blocking Peptide (the C terminal of FAM175A)(100ug)
FAM175A (family with sequence similarity 175, member A ) Blocking Peptide (the C terminal of FAM175A)(100ug)

FAM175A (family with sequence similarity 175, member A ) Blocking Peptide (the C terminal of FAM175A)(100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-FAM175A Antibody (ARP65319_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP65319
Size: 100ug
Weight: 47kDa
Gene: 84142
Format: Lyophilized powder
Target: FAM175A is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
Alternative names: ABRA1; CCDC98; FLJ11520; FLJ12642; FLJ13614
See Full Product Listings >