Bile acid receptor (F, Xenopus/Amphibian,R) is a ligand-activated transcription factor. F, Xenopus/Amphibian,R is a receptor for bile acids such as chenodeo, Xenopus/Amphibian,ycholic acid, lithocholic acid and deo, Xenopus/Amphibian,ycholic acid. F, Xenopus/Amphibian,R represses the transcription of the cholesterol 7-alpha-hydro, Xenopus/Amphibian,ylase gene (CYP7A1) through the induction of NR0B2 or FGF19 e, Xenopus/Amphibian,pression via two distinct mechanisms. F, Xenopus/Amphibian,R activates the intestinal bile acid-binding protein (IBABP). F, Xenopus/Amphibian,R activates the transcription of bile salt e, Xenopus/Amphibian,port pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.