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Esrp2 (epithelial splicing regulatory protein 2 ) Blocking Peptide (the N terminal of Esrp2)(100ug)

Esrp2 (epithelial splicing regulatory protein 2 ) Blocking Peptide (the N terminal of Esrp2)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Esrp2 Antibody (ARP37937_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human, Mouse
Presku: AAP37937
Size: 100ug
Weight: 77kDa
Gene: 77411
Format: Lyophilized powder
Target: Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Alternative names: 9530027K23Rik; Rbm35b
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