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ERK2 (4C11) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252672

ERK2 (4C11) Antibody

ERK2 (E, Xenopus/Amphibian,tracellular-signal-related kinase 2 or mitogen-activated protein kinase 1) is a 360-amino acid protein (~40kDa), belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon e, Xenopus/Amphibian,tracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.

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SPECIFICATIONS

Catalog Number

252672

Size

0.1 mg

Applications

IF, IHC

Reactivities

Hum, Mouse

Format

Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human ERK2 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG2a

Accession

P28482

Clonality

4C11

Additional Info

Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; E, Xenopus/Amphibian,tracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; ERK2; PRKM1; PRKM2; MAPK1

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