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ERK/MAPK Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253135

ERK/MAPK Antibody

The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases,Porcine44 and p42 encoded by ERK1 and ERK2 respectively. Both kinases are regulated by dual specific phosphorylation on tyrosine and threonine in response to insulin and NGF. ERK/MAPK is involved in both the initiation and regulation of meiosis,Mouse,itosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. The activity of ERK/MAPK is regulated by dual phosphorylation at Thr202 and Tyr204.

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SPECIFICATIONS

Catalog Number

253135

Size

0.1 ml

Applications

WB

Reactivities

Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat ERK/MAPK.

Isotype

Rabbit Ig

Accession

P63086

Additional Info

ERK-1; Mitogen-activated protein kinase 3; E, Xenopus/Amphibian,tracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAPK1; p44-ERK1; ERT2; p44-MAPK; Microtubule-associated protein 2 kinase; MAPK3; ERK1; PRKM3; and for ERK-2; Mitogen-activated protein kinase 1; E, Xenopus/Amphibian,tracellular signal-regulated kinase 2; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK2; p42-MAPK; ERT1; MAPK1; ERK2; PRKM1; PRKM2

SUPPLIER INFO

ABBIOTEC

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