
Supplier:
Aviva Systems Biology IncorporatedEpstein-Barr gp125 Virus Antigen Protein (1ml)
Inactivation: detergent disruption
Introduction: Epstein-Barr Virus (EBV) is one of the most common and widely disseminated human viruses, and is the etiological agent of infectious mononucleosis (IM). IM, also called 'Kissing DiseaseпїЅ because of its prevalence in young adults, may vary from mild to severe - but it is rarely fatal. Mononucleosis must be distinguished from a variety of other infectious diseases that cause fever and inflammation of the upper respiratory tract. A syndrome similar to EBV-induced mononucleosis may be the result of a Cytomegalovirus or Toxoplasma infection.
Epstein-Barr Virus antigen, product #8180 is prepared from a detergent extraction of P3HR-1 or P3H3 cells that have been induced by the use of TPA and sodium butyrate to produce viral proteins. EBV gp125 is purified from this extract by affinity chromatography using a monoclonal antibody specific to the gp125 protein.
Serologic tests are an important aid in diagnosis of EBV infection. The presence of IgG antibody to capsid antigen and to the Epstein-Barr nuclear antigen (EBNA) indicates past infection. Current infection is usually detected by presence of IgM antibody to EBV capsid antigen (gp125).
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ELISA, WB
Hosts
Mouse
Applications
IHC
Hosts
Mouse
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