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EphB6 (8E7H) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252648

EphB6 (8E7H) Antibody

EphB6 (EPH receptor B6) is a 1006-amino acid protein (~110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is e, Xenopus/Amphibian,pressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.

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SPECIFICATIONS

Catalog Number

252648

Size

0.1 mg

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of EphB6 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

O15197

Clonality

8E7H12

Additional Info

Ephrin type-B receptor 6; HEP; Tyrosine-protein kinase-defective receptor EPH-6; EPHB6

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