EphB3 (4A12) Antibody

EphB3 (EPH receptor B3) is a member of ephrin receptors. Ephrin receptors and their ligands, the ephrins,Mouse,ediate numerous developmental processes,Porcinearticularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their e, Xenopus/Amphibian,tracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.