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EPAC1 Recombinant Protein (0.05 mg)

EPAC1 Recombinant Protein (0.05 mg)

EPAC1, also known as Rap guanine nuclear exchange factor 3 and cAMPGEF-I, is expressed most prominently in brain, heart, kidney, pancreas, spleen, ovary, thyroid and spinal chord. Epac1 is a cAMP-binding protein with intrinsic guanine nuclear exchange factor activity that couples cAMP production to the activation of Rap, a GTPase belonging to the Ras family. This activation of Rap influeces numerous cellular processes such as integrin-mediated cell adhesion, vascular endothelial barrier formation, and cardiac myocyte gap junction formation. Recently, Epac1 has been suggested to also be involved in the cAMP-dependent regulation of ion channel formatioon, intracellular Ca++ signalling, ion transporter activity, and exocytosis.

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SPECIFICATIONS

Size

0.05 mg

Applications

ELISA, WB

Presku

OPPB00460

Weight

19 kDa (Calculated)

SUPPLIER INFO

Aviva Systems Biology Incorporated

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