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EP300 (7D8A) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252813

EP300 (7D8A) Antibody

EP300 (E1A binding protein p300) is an adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It is a histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. p300 has also been identified as a co-activator of HIF1A (hypo, Xenopus/Amphibian,ia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypo, Xenopus/Amphibian,ia-induced genes such as VEGF. Defects in this protein cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

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SPECIFICATIONS

Catalog Number

252813

Size

0.1 ml

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of EP300 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q7Z6C1

Clonality

7D8A6

Additional Info

EP300 protein; p300; KAT3B

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