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EP300 (7D8A) Antibody

EP300 (7D8A) Antibody

Cat no: 252813


Supplier: ABBIOTEC
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EP300 (E1A binding protein p300) is an adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It is a histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. p300 has also been identified as a co-activator of HIF1A (hypo, Xenopus/Amphibian,ia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypo, Xenopus/Amphibian,ia-induced genes such as VEGF. Defects in this protein cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Catalogue number: 252813
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: Q7Z6C1
Antigen: Purified recombinant fragment of EP300 e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 7D8A6
Additional info: EP300 protein; p300; KAT3B