Supplier:
Aviva Systems Biology IncorporatedENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2) Blocking Peptide (the N terminal of ENPP2)(100ug)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP44907
Target
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Weight
95kDa
Gene Id
5168
Alternative Names
ATX; ATX-X; FLJ26803; LysoPLD; NPP2; PD-IALPHA; PDNP2
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