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Endothelin B Receptor Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 251852

Endothelin B Receptor Antibody

The endothelin receptor B (EDNRB) is a non-specific receptor for endothelin 1, 2 and 3. EDNRB mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Defects in the endothelin receptor B are a cause of Waardenburg syndrome type 4A (WS4A), also known as Waardenburg-Shah syndrome. WS4A is characterized by the association of Waardenburg features (depigmentation and deafness) and the absence of enteric ganglia in the distal part of the intestine (Hirschprung disease).

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SPECIFICATIONS

Catalog Number

251852

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA, 0.05% thimerosal with 0.5% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human endothelin B receptor.

Isotype

Rabbit Ig

Accession

P24530

Additional Info

Endothelin B receptor; ET-BR; ET-B; Endothelin receptor non-selective type; EDNRB; ETRB

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