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EME1 (essential meiotic endonuclease 1 homolog 1 (S. pombe)) Blocking Peptide (the middle region of protein) (100ug)

EME1 (essential meiotic endonuclease 1 homolog 1 (S. pombe)) Blocking Peptide (the middle region of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-EME1 antibody (Catalogue #: ARP52988_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP52988
Size: 100 ug
Weight: 63kDa
Gene: 146956
Format: Lyophilized powder
Target: EME1 interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. EME1 may be required in mitosis for the processing of stalled or collapsed replication forks.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM].
Alternative names: FLJ31364; MMS4L
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