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EMAP-II Recombinant Protein (0.005 mg)

EMAP-II Recombinant Protein (0.005 mg)

EMAP-II is a tumor derived cytokine that exerts a wide range of activities on endothelial cells, monocytes and neutrophils. EMAP-II inhibits endothelial cell proliferation, vasculogenesis, neovessel formation, and can induce apoptosis. It is also chemotactic towards neutrophils and monocytes and induces myeloperoxidase activity from neutrophils. Of clinical importance, EMAP-II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues. Mature EMAP-II is an 18.3 kDa protein, which is synthesized as the C-terminal portion of a biologically inactive precursor protein containing a propeptide of 146 amino acid residues. Recombinant human EMAP-II is an 18.3 kDa protein consisting of 166 amino acid residues.

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SPECIFICATIONS

Size

0.005 mg

Presku

OPPB00089

Alternative Names

Endothelial-Monocyte Activating Polypeptide II

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