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ELOVL6 Antibody (OAPB00668)

ELOVL6 Antibody (OAPB00668)

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB00668

Target

Elongation of very long chain fatty acids protein 6

Alternative Names

ELOVL6; Elongation of very long chain fatty acids protein 6; hELO2; Fatty acyl-CoA elongase; FACE; Long-chain fatty-acyl elongase; LCE

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