Presku: | AAP38813 |
Size: | 100 ug |
Weight: | 68kDa |
Gene: | 8178 |
Format: | Lyophilized powder |
Target: | ELL was shown to encode a previously uncharacterized elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. Functionally, ELL resembles Elongin (SIII), a transcription elongation factor regulated by the product of the von Hippel-Lindau (VHL) tumor suppressor gene. |