Supplier:
Aviva Systems Biology IncorporatedELF3 (E74-like factor 3) Blocking Peptide (100ug)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100 ug
Format
Lyophilized powder
Presku
AAP36846
Target
Elf3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. It acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity). It also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. IT represses KRT4 promoter activity (By similarity). It may play an important role in epithelial cell differentiation and tumorigenesis and may be a critical downstream effector of the ERBB2 signaling pathway (By similarity). It may be associated with mammary gland development and involution. It plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
Weight
41kDa
Gene Id
13710
Alternative Names
ESE-1, ESX, jen
SUPPLIER INFO
Applications
ELISA, WB
Hosts
Mouse
Applications
IHC
Hosts
Mouse
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