Presku: | AAP48176 |
Size: | 100 ug |
Weight: | 52kDa |
Gene: | 3646 |
Format: | Lyophilized powder |
Target: | EIF3E belongs to the eIF-3 subunit E family.It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3E is required for nonsense-mediated mRNA decay (NMD); It may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. The protein may interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins. |
Alternative names: | EIF3-P48; EIF3S6; INT6; eIF3-p46 |